Please login to your online account to display your discounted pricing

CD87 (UPAR) Mouse anti-Human, PerCP-eFluor 710, Clone: VIM5, eBioscience™

Mouse Monoclonal Antibody

$409.14 - $549.55

Specifications

Antigen CD87 (UPAR)
Clone VIM5
Host Species Mouse
Gene Alias Urokinase plasminogen activator receptor, UPA Receptor
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123808

 
affymetrix
46387942
100 tests Each for $549.55

501130805

 
affymetrix
46-3879-41
25 tests Each for $409.14
Description & Specifications

Specifications

Antigen CD87 (UPAR)
Clone VIM5
Host Species Mouse
Gene Alias Urokinase plasminogen activator receptor, UPA Receptor
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PerCP-eFluor 710
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

This VIM5 monoclonal antibody reacts with human CD87, a GPI-linked receptor for urokinase plasminogen activator (uPA). By sequestering uPA, CD87 is involved in the conversion of plasminogen to plasmin on the leading edge of migrating cells, a process critical for chemotaxis. CD87 is expressed on the surface of monocytes, dendritic cells, and on activated T and NK cells. Interestingly, in granulocytes, CD87 expressed in the cytoplasm and on the cell surface. Non-hematopoietic cells such as endothelial cells, keratinocytes, and fibroblasts, also express this receptor. Finally, CD87 plays a role in cell adhesion and migration, angiogenesis, and tumor metastasis.

This monoclonal antibody has been reported to have neutralization activity.