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CD86 (B7-2) Rat anti-Mouse, Clone: GL1, eBioscience™

Rat Monoclonal Antibody

$85.55 - $317.55

Specifications

Antigen CD86 (B7-2)
Clone GL1
Host Species Rat
Gene Alias B72, B7.2, B70, Ly-58
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122653

 
affymetrix
14086285
500μg Each for $317.55

5012735

 
affymetrix
14086281
50μg Each for $85.55

5012736

 
affymetrix
14086282
100μg Each for $172.55
Description & Specifications

Specifications

Antigen CD86 (B7-2)
Clone GL1
Host Species Rat
Gene Alias B72, B7.2, B70, Ly-58
Species Reactivity Mouse
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry (Frozen)
Applications Immunoprecipitation
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The GL1 monoclonal antibody reacts with mouse CD86, an ∽80kDa surface receptor also known as B7-2. CD86 & CD80 are members of the B7 family of costimulatory molecules. CD86 is expressed at low level on B cells, macrophages, and dendritic cells and is upregulated on B cells through a variety of surface stimuli including the BCR complex, CD40 and some cytokine receptors. CD86 is also expressed by activated mouse T cells and thioglycolate-elicited peritoneal cells. In addition to CD80 (B7-1), CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152 (CTLA-4). This interaction plays a critical role in T-B crosstalk, T cell costimulation, autoantibody production and Th2-mediated Ig production. The kinetics of upregulation of CD86 upon stimulation, supports its major contribution during the primary phase of an immune response.