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CD86 (B7-2) Mouse anti-Rat, FITC, Clone: 24F, eBioscience™

Mouse Monoclonal Antibody

$117.48 - $223.08

Specifications

Antigen CD86 (B7-2)
Clone 24F
Host Species Murine
Gene Alias B72
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
509684 Life Technologies
LS11086081
50μg Each for $117.48
509685 Life Technologies
LS11086082
100μg Each for $223.08
Specifications

Description

The 24F monoclonal antibody reacts with rat CD86, an ∽90kDa surface receptor, also known as B7-2. CD86 and CD80 are members of the B7 family of costimulatory molecules. CD86 is expressed by germinal center B cells and at low levels on macrophages, dendritic cells and non-lymphoid cells in the thymus. Its expression is upregulated on B cells through a variety of surface stimuli including LPS. In addition to CD80 (B7-1), CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152 (CTLA-4). The interaction of CD86 with its ligands plays a critical role in T-B crosstalk, T cell costimulation, autoantibody production and Th2-mediated Ig production. The kinetics of upregulation of CD86 upon stimulation supports its major contribution during the primary phase of an immune response.
Description & Specifications

Specifications

CD86 (B7-2)
Murine
Flow Cytometry
FITC
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.5mg/mL
24F
B72
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer