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CD85k (ILT3) Mouse anti-Human, Clone: ZM4.1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

$158.05 - $535.05

Specifications

Antigen CD85k (ILT3)
Clone ZM4.1
Host Species Mouse
Gene Alias ILT-3, LIR5, LILRB4, HM18, GM 4d
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014552

 
affymetrix
16-5139-81
50μg Each for $158.05

5014553

 
affymetrix
16513985
500μg Each for $535.05
Description & Specifications

Specifications

Antigen CD85k (ILT3)
Clone ZM4.1
Host Species Mouse
Gene Alias ILT-3, LIR5, LILRB4, HM18, GM 4d
Species Reactivity Human
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The monoclonal antibody ZM4.1 recognizes ILT3, also known as CD85k. ILT3 is a member of the large family of ILT molecules (Immunologulin-like Transcripts, Leucocyte Ig-like Receptors (LIRs) and Monocyte/Macrophage Ig-like Receptors (MIRs). ILT3 is a 60kDa transmembrane protein with two Ig domains and ITIMs. Expression is found on monocytes, macrophages, and dendritic cells. High levels of ILT3 expression is also found on plasmacytoid dendritic cells (pDCs). ILT3 expression by DCs has been shown to be required to induce Regulatory Tcells (tregs). Addition of ZM4.1, like ZM3.8, blocks the suppressive function of the Tregs in in vitro culture systems with allogenic DC’s.