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CD85k (ILT3) Mouse anti-Human, APC, Clone: ZM4.1, eBioscience™

Mouse Monoclonal Antibody

$216.05 - $419.05

Specifications

Antigen CD85k (ILT3)
Clone ZM4.1
Host Species Mouse
Gene Alias LIR5, LILRB4, HM18, GM 4d
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5015189

 
affymetrix
17-5139-41
25 tests Each for $216.05

5015190

 
affymetrix
17513942
100 tests Each for $419.05
Description & Specifications

Specifications

Antigen CD85k (ILT3)
Clone ZM4.1
Host Species Mouse
Gene Alias LIR5, LILRB4, HM18, GM 4d
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.125μg)/test

The monoclonal antibody ZM4.1 recognizes ILT3, also known as CD85k. ILT3 is a member of the large family of ILT molecules (Immunologulin-like Transcripts, Leucocyte Ig-like Receptors (LIRs) and Monocyte/Macrophage Ig-like Receptors (MIRs). ILT3 is a 60kDa transmembrane protein with two Ig domains and ITIMs. Expression is found on monocytes, macrophages, and dendritic cells. High levels of ILT3 expression is also found on plasmacytoid dendritic cells (pDCs). ILT3 expression by DCs has been shown to be required to induce Regulatory Tcells (tregs). Addition of ZM4.1, like ZM3.8, blocks the suppressive function of the Tregs in in vitro culture systems with allogenic DC’s.