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CD85g (ILT7) Mouse anti-Human, PE, Clone: eBio17G10.2 (17G10.2), eBioscience™

Mouse Monoclonal Antibody

$183.48 - $381.48

Specifications

Antigen CD85g (ILT7)
Clone eBio17G10.2 (17G10.2)
Host Species Murine
Gene Alias ILT-7, LILRA4
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5010809 Life Technologies
LS12517941
25 Tests Each for $183.48
5010810 Life Technologies
LS12517942
100 Tests Each for $381.48
Specifications

Description

The eBio17G10.2 monoclonal antibody reacts with human immunoglobulin-like transcript 7 (ILT7), also known as CD85g. ILT7 is part of the leukocyte immunoglobulin-like receptor (LIR) gene family and associates with Fc epsilon R1 gamma to form a functional complex which transduces ITAM-mediated signals that negatively modulates TLR-induced type I IFN production by human plasmacytoid dendritic cells. ILT7 is expressed exclusively on plasmacytoid dendritic cells and is absent in monocyte derived DCs. Treatment with IL-3 or CpG causes a decrease in expression.

Double staining of human PBMCs with eBio17G10.2 and anti-pDC marker BDCA2 yields virtually complete co-staining. Cross linking of ILT7 with eBio17G10.2 antibody causes reduced transcription of IFN alpha1, IFN alpha2, IFN alpha4 and IFN beta.
Description & Specifications

Specifications

CD85g (ILT7)
Murine
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
eBio17G10.2 (17G10.2)
ILT-7, LILRA4
Flow Cytometry
PE
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.125μg)/test