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CD85d (ILT4) Rat anti-Human, APC, Clone: 42D1, eBioscience™

Rat Monoclonal Antibody

Manufacturer:  Life Technologies LS17514942

Catalog No. 501129155



Description

Description

Description: The monoclonal antibody 42D1 recognizes the CD85d protein also known as ILT4, LIR-2. It is a member of the ILT (immunoglobulin-like transcript)/ LIR (leukocyte Ig-like receptor), MIR (monocytes Ig-like receptor) family. CD85d is a 110 kDa sin

Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered. This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

CD85d (ILT4)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q8N423
CD85d, ILT4, LIR2, MIR10, CD85 antigen-like family member D, CD85d antigen, Ig-like transcript 4, ILT-4, ILT4CD85d, Immunoglobulin-like transcript 4, Leukocyte immunoglobulin-like receptor 2, leukocyte immunoglobulin-like receptor subfamily B member 2, leukocyte immunoglobulin-like receptor subfamily B member 2 soluble isoform, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), LIR2CD85D, LIR-2subfamily A (with TM domain), member 6, member 2, MIR10LILRA6, Monocyte/macrophage immunoglobulin-like receptor 10
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
42D1
APC
LILRB2
Liquid
LILRB2
IgG2a, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
10288
Documents

For Research Use Only.