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Thermo Scientific™ Lab Vision™ CD81/TAPA-1 Ab-1, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry, immunofluorescence, flow cytometry and functional study experiments.

Manufacturer: thermo scientific™ lab vision™  MS502P1ABX

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Catalog No. MS502P1ABX

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Description & Specifications

Specifications

Antigen CD81/TAPA-1 Ab-1
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Classification Monoclonal
Clone 1.3.3.22
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Immunogen B cell line derived from a Burkitt lymphoma
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline Signal Transduction
Type Primary

Ensure accurate, reproducible results in immunohistochemistry, immunofluorescence, flow cytometry and functional study experiments with Thermo Scientific™ CD81/TAPA-1 Ab-1, Mouse Monoclonal Antibody.

CD81 (target of anti-proliferative antibody-1 (TAPA-1) has a very broad cellular distribution, being expressed on T and B lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.

Host Species: Mouse

Clone: 1.3.3.22

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: B-cell line derived from a Burkitt lymphoma

Molecular Weight: 24 kDa

Positive Control: Daudi, Raji, U266, HUT-78, HUT-102, Jurkat, HL-60, KG1a, A293, A431, MG63, and human lymphocytes; Tonsil/lymph node

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Acetone-fixed frozen)
  • Immunofluorescence
  • Flow Cytometry
  • Functional Study

Note:

USA: RUO; Int'l: RUO