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CD8 Mouse anti-Human, Clone: OKT8 (OKT-8), Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

$158.05 - $477.05

Specifications

Antigen CD8
Clone OKT8 (OKT-8)
Host Species Murine
Gene Alias CD8 alpha, leu-2a
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5014217 Life Technologies
LS16008681
50μg Each for $158.05
5014218 Life Technologies
LS16008685
500μg Each for $477.05
Specifications

Description

The OKT8 monoclonal antibody reacts with the human CD8a molecule, an approximately 32-34kDa cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8 αβ) or as a homodimer (CD8 αα). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T-cell development and activation of mature T cells. Preliminary testing indicates that OKT8 and two other mouse anti-human CD8 antibodies (clone RPA-T8, Cat. No.14-0088 and clone HIT8a, Cat. No.14-0089) do not compete with each other for binding to human peripheral blood leukocytes by flow cytometric analysis, suggesting that they do not bind to similar epitopes or block each other by steric hindrance.
Description & Specifications

Specifications

CD8
Murine
Human
RUO
Purified
Primary
aqueous buffer, no sodium azide
OKT8 (OKT-8)
CD8 alpha, leu-2a
Flow Cytometry
Unlabeled
Store at 2-8°C.
Monoclonal