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CD79a Mouse, PE, Clone: HM47, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $332.05

Specifications

Antigen CD79a
Clone HM47
Host Species Mouse
Gene Alias Ig-alpha, mb-1
Species Reactivity Baboon, Canine, Chicken, Chimpanzee, Cow, Guinea Pig, Horse, Human, Mouse, Non-human primate, Pig, Rat, Rhesus Ma
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010474

 
affymetrix
12-0792-41
25 tests Each for $187.05

5010475

 
affymetrix
12-0792-42
100 tests Each for $332.05
Description & Specifications

Specifications

Antigen CD79a
Clone HM47
Host Species Mouse
Gene Alias Ig-alpha, mb-1
Species Reactivity Baboon, Canine, Chicken, Chimpanzee, Cow, Guinea Pig, Horse, Human, Mouse, Non-human primate, Pig, Rat, Rhesus Ma
Applications Flow Cytometry (Intracellular Staining)
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.06μg)

The monoclonal antibody HM47 recognizes the cytoplasmic domain of CD79a, also known as mb-1. CD79a is a 47kDa membrane glycoprotein that associates with CD79b to form the heterodimeric B cell receptor (BCR). This receptor is responsible for B cell signaling, resulting in activation, apoptosis or anergy. Expression of CD79a is found throughout development from the earliest pre-B cell to plasma cells. CD79 is expressed on B cell neoplasms and some non-B cell malignancies such as AML. Unlike other antibodies that can be masked in B cell neoplastic cells, HM47 is a reliable antibody for recognizing CD79a and, as such, is a good marker for B cells. Because several variants of CD79a exist, the exact location of the epitope may differ slightly. Nevertheless, in humans thie epitope is typically amino acids 208-222.

The HM47 antibody reacts to human, mouse, rat, dog, primates (rhesus, chimpanzee, macaque and baboon) pig, guinea rabbit, pig, horse, cow and chicken.