Please login to your online account to display your discounted pricing

CD79 Mouse anti-Mouse, Clone: 24C2.5, eBioscience™

Mouse Monoclonal Antibody

$85.55 - $172.55

Specifications

Antigen CD79
Clone 24C2.5
Host Species Mouse
Gene Alias Ig-alpha, mb-1, Ly-54
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5012704

 
affymetrix
14079180
25μg Each for $85.55

5012705

 
affymetrix
14079182
100μg Each for $172.55
Description & Specifications

Specifications

Antigen CD79
Clone 24C2.5
Host Species Mouse
Gene Alias Ig-alpha, mb-1, Ly-54
Species Reactivity Mouse
Applications Immunohistochemistry
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This 24C2.5 monoclonal antibody reacts with the intracellular tail of mouse CD79a (also known as Ig alpha or mb-1), a signaling component of the B cell receptor (BCR). CD79a heterodimerizes with CD79b (Ig beta, B29), and together with surface Ig, make up the BCR. Both CD79 subunits consist of a single extracellular Ig domain, a transmembrane domain, and an intracellular signaling domain. CD79a is expressed almost exclusively on B cells, as well as in most B lineage acute lymphoblastic leukemias. The cytoplasmic domain of CD79a contains immunoreceptor tyrosine-based activation motifs (ITAMs), which constitute the signal transducing portions of the BCR. Tyrosine phosphorylation of these ITAMs by Syk and Lyn initiates numerous signaling cascades, resulting in B cell activation, proliferation, and differentiation.