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CD79 Mouse anti-Mouse, Clone: 24C2.5, eBioscience™

Mouse Monoclonal Antibody

$85.55 - $172.55

Specifications

Antigen CD79
Clone 24C2.5
Host Species Murine
Gene Alias Ig-alpha, mb-1, Ly-54
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5012704 Life Technologies
LS14079180
25μg Each for $85.55
5012705 Life Technologies
LS14079182
100μg Each for $172.55
Specifications

Description

This 24C2.5 monoclonal antibody reacts with the intracellular tail of mouse CD79a (also known as Ig alpha or mb-1), a signaling component of the B cell receptor (BCR). CD79a heterodimerizes with CD79b (Ig beta, B29), and together with surface Ig, make up the BCR. Both CD79 subunits consist of a single extracellular Ig domain, a transmembrane domain, and an intracellular signaling domain. CD79a is expressed almost exclusively on B cells, as well as in most B lineage acute lymphoblastic leukemias. The cytoplasmic domain of CD79a contains immunoreceptor tyrosine-based activation motifs (ITAMs), which constitute the signal transducing portions of the BCR. Tyrosine phosphorylation of these ITAMs by Syk and Lyn initiates numerous signaling cascades, resulting in B cell activation, proliferation, and differentiation.
Description & Specifications

Specifications

CD79
Murine
Mouse
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
24C2.5
Ig-alpha, mb-1, Ly-54
Immunohistochemistry,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL