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CD7 Mouse anti-Human, APC, Clone: 4H9, eBioscience™

Mouse Monoclonal Antibody

$143.55 - $361.05

Specifications

Antigen CD7
Clone 4H9
Host Species Mouse
Gene Alias Leu-9
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014867

 
affymetrix
17-0078-41
25 tests Each for $143.55

5014868

 
affymetrix
17007842
100 tests Each for $361.05
Description & Specifications

Specifications

Antigen CD7
Clone 4H9
Host Species Mouse
Gene Alias Leu-9
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

This 4H9 monoclonal antibody reacts with human CD7 (also known as Leu-9 or gp40), a 40kDa transmembrane glycoprotein belonging to the immunoglobulin superfamily. This molecule is expressed on peripheral blood T lymphocytes and natural killer cells, as well as on lymphoid and myeloid lineage precursors during adult hematopoiesis. Capable of providing a costimulatory signal and associating with CD3 and CD45, CD7 is involved in T cell activation.

CD7 has also been detected on numerous T cell-derived leukemias and lymphomias. In fact, because CD7 expression is greater on CD4+ T cells in classical Hodgkin’s lymphoma than in benign reactive lymph adenopathy, this molecule may be used as a diagnostic for Hodgkin’s lymphoma.

Blocking assays demonstrate that this clone recognizes the same epitope as clone 124-1D1.