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CD68 Rat anti-Mouse, Clone: FA-11, eBioscience™

Rat Monoclonal Antibody

$106.92 - $267.96

Specifications

Antigen CD68
Clone FA-11
Host Species Rat
Gene Alias macrosialin, gp110
Applications Flow Cytometry (Intracellular Staining),Immunohistochemistry (Frozen)
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122647 Life Technologies
LS14068180
25μg Each for $106.92
501129259 Life Technologies
LS14068182
100μg Each for $267.96
Specifications

Description

This FA-11 monoclonal antibody reacts with mouse CD68, known also as macrosialin. CD68 is a heavily O- and N- glycosylated type I integral membrane protein belonging to the sialomucin family and is closely related to the Lysosomal/endosomal-Associated Membrane Glycoproteins (LAMP). Although commonly used as a pan-macrophage marker, low levels of expression have also been observed in Langerhans cells and conventional dendritic cells. CD68 is mostly localized in the late endosomes and lysosomes with a smaller fraction circulating to the cell surface. In the steady state, only about 10-15% of CD68 is present at the surface. Cell stimulation increases expression of CD68, its transport to cell surface, and results in glycoform remodeling. CD68 binds oxidized LDL and is involved in the process of phagocytosis.

The FA-11 antibody is not recommended for use in immunohistochemistry of formalin-fixed paraffin embedded tissues.
Description & Specifications

Specifications

CD68
Rat
Flow Cytometry (Intracellular Staining),Immunohistochemistry (Frozen)
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL
FA-11
macrosialin, gp110
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer