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CD68 Mouse anti-Human, Clone: KP1, eBioscience™

Mouse Monoclonal Antibody

$106.92 - $146.52

Specifications

Antigen CD68
Clone KP1
Host Species Murine
Gene Alias Macrosialin
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



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Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122650 Life Technologies
LS14068880
25μg Each for $106.92
501122651 Life Technologies
LS14068882
100μg Each for $146.52
Specifications

Description

The KP1 antibody reacts with human CD68 which belongs to the sialomucin family and is closely related to the family of lysosomal-associated membrane proteins (lamps) and scavenger receptor. CD68 is predominantly an intracellular protein, found mainly in the late endosomal compartment but can be detected in smaller amounts on the surface of mainly myeloid-derived cells; monocytes and macrophages, dendritic cells (and in some langerhan cells), neutrophils, basophils, mast cells, myeloid progenitor cells, and a subset of CD34+ hematopoietic bone marrow progenitor cells. The function has not been fully elucidated but based on homology and structure, CD68 may play a role in antigen processing or presentation and protection of the lysosomal membrane from hydrolytic enzymes. Reports have also shown expression in activated T cells, and about 40% of peripheral blood B-lymphocytes and 50% of all B-ALL. The KP1 antibody has also been reported to stain fibroblasts which may be due to a conserved epitope rather than fibroblasts expressing CD68.
Description & Specifications

Specifications

CD68
Murine
Human
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
KP1
Macrosialin
Flow Cytometry,Immunohistochemistry (Formalin/Paraffin),Immunohistochemistry (Frozen),Immunoprecipitation,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL