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CD68 Mouse anti-Human, Clone: 815CU17, eBioscience™

Mouse Monoclonal Antibody

$117.45 - $265.35

Specifications

Antigen CD68
Clone 815CU17
Host Species Murine
Species Reactivity Human
Applications Immunohistochemistry (Formalin/Paraffin),Microscopy,Western Blot
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122648 Life Technologies
LS14068780
25μg Each for $117.45
501122649 Life Technologies
LS14068782
100μg Each for $265.35
Specifications

Description

This 815CU17 monoclonal antibody reacts with human CD68, a 110 kDa, transmembrane glycoprotein that belongs to the sialomucin family and is closely related to the lysosomal-associated membrane proteins (LAMP) and scavenger receptor. CD68 is predominantly an intracellular protein, found mainly in the late endosomal compartment but can be detected in smaller amounts on the surface of mainly myeloid-derived cells: monocytes, macrophages, dendritic cells (and in some langerhans cells), neutrophils, basophils, mast cells, myeloid progenitor cells, and a subset of CD34+ hematopoietic bone marrow progenitor cells. The function has not been fully elucidated but based on homology and structure, CD68 may play a role in antigen processing or presentation and protection of the lysosomal membrane from hydrolytic enzymes. Reports have also shown expression in activated T cells, and about 40% of peripheral blood B lymphocytes and 50% of all B-ALL.

This 815CU17 antibody does not cross-react with mouse or rat CD68.

For flow cytometric analysis of human CD68, we recommend clone eBioY1/82A.
Description & Specifications

Specifications

CD68
Murine
Immunohistochemistry (Formalin/Paraffin),Microscopy,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL
815CU17
Human
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer