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CD68 Mouse anti-Human, Clone: 815CU17, eBioscience™

Mouse Monoclonal Antibody

$114.55 - $259.55

Specifications

Antigen CD68
Clone 815CU17
Host Species Mouse
Species Reactivity Human
Applications Immunohistochemistry (Formalin/Paraffin)
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122648

 
affymetrix
14068780
25μg Each for $114.55

501122649

 
affymetrix
14068782
100μg Each for $259.55
Description & Specifications

Specifications

Antigen CD68
Clone 815CU17
Host Species Mouse
Species Reactivity Human
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Microscopy
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

This 815CU17 monoclonal antibody reacts with human CD68, a 110 kDa, transmembrane glycoprotein that belongs to the sialomucin family and is closely related to the lysosomal-associated membrane proteins (LAMP) and scavenger receptor. CD68 is predominantly an intracellular protein, found mainly in the late endosomal compartment but can be detected in smaller amounts on the surface of mainly myeloid-derived cells: monocytes, macrophages, dendritic cells (and in some langerhans cells), neutrophils, basophils, mast cells, myeloid progenitor cells, and a subset of CD34+ hematopoietic bone marrow progenitor cells. The function has not been fully elucidated but based on homology and structure, CD68 may play a role in antigen processing or presentation and protection of the lysosomal membrane from hydrolytic enzymes. Reports have also shown expression in activated T cells, and about 40% of peripheral blood B lymphocytes and 50% of all B-ALL.

This 815CU17 antibody does not cross-react with mouse or rat CD68.

For flow cytometric analysis of human CD68, we recommend clone eBioY1/82A.