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CD66a (CEACAM1) Mouse anti-Mouse, Clone: CC1, eBioscience™

Mouse Monoclonal Antibody

$129.05 - $361.05

Specifications

Antigen CD66a (CEACAM1)
Clone CC1
Host Species Mouse
Gene Alias CEACAM, BGP, biliary glycoprotein
Species Reactivity Mouse
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5012681

 
affymetrix
14066180
25μg Each for $129.05

5012682

 
affymetrix
14066182
100μg Each for $361.05
Description & Specifications

Specifications

Antigen CD66a (CEACAM1)
Clone CC1
Host Species Mouse
Gene Alias CEACAM, BGP, biliary glycoprotein
Species Reactivity Mouse
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry (Formalin/Paraffin)
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The monoclonal antibody CC1 recognizes CD66a, also known as carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), biliary glycoprotein, and BPG. Expression of CD66a is found on brush borders, epithelial, and endothelial cells. In hematopoietic cells expression is found abundantly on B cells, as well as some NKs, monocytes, DCs, and granulocytes. Although low levels of mRNA have been identified in T cells in humans, resting mouse T lymphocytes are not reported to express CD66a, as confirmed by lack of staining with CC1 antibody. In humans, expression levels of CD66a have been used to identify malignancies. CD66a plays a key role as a regulator of BCR activation of B lymphocytes.

An alternate allele, CEACAM1b, is expressed in SJL mice; therefore, CC1 does not stain SJL tissue. The monoclonal CC1 has been shown to block viral infection and also enhance B cell proliferation when combined with IgM crosslinking.