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CD66a (CEACAM1) Mouse anti-Human, APC, Clone: CD66a-B1.1, eBioscience™

Mouse Monoclonal Antibody

$158.05 - $404.55

Specifications

Antigen CD66a (CEACAM1)
Clone CD66a-B1.1
Host Species Mouse
Gene Alias CEACAM1, CEACAM3, CEACAM6, CEA
Species Reactivity Human
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

50245656

 
affymetrix
17066841
25 tests Each for $158.05

50245657

 
affymetrix
17066842
100 tests Each for $404.55
Description & Specifications

Specifications

Antigen CD66a (CEACAM1)
Clone CD66a-B1.1
Host Species Mouse
Gene Alias CEACAM1, CEACAM3, CEACAM6, CEA
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.06μg)/test

The CD66a-B1.1 monoclonal antibody reacts with human CD66a, c, d, and e, which are also known as CEACAM1, CEACAM6, CEACAM3 and CEA, respectively. CD66 is expressed on endothelial and epithelial cells, as well as on neutrophils and monocytes. Myeloma and cancer cells also express CD66. Moreover, expression of this receptor can be induced on T cells, B cells, and CD16-negative NK cells. CD66 exists as multiple splice variants that differ in the length of their cytoplasmic domain, which contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that mediates the inhibitory functions of this cell surface protein on T and NK cells. CD66 is involved in cell adhesion and growth, neutrophil activation, and signaling. Finally, studies have shown that the CD66 variants interact with each other homo- and heterotypically.