missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

CD64 (Fc gamma Receptor 1) Mouse anti-Human, Functional Grade, Clone: 10.1, eBioscience™

Mouse Monoclonal Antibody

Manufacturer:  Life Technologies LS16064985

 View more versions of this product

Catalog No. 501129467



Description

Description

Description: The 10.1 monoclonal antibody reacts with human CD64 (FcRI), a 75 kDa type I transmembrane protein. CD64 is the high affinity receptor for IgG and is involved in antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, and regulation of cytokine production. Monocytes and macrophages express CD64, while mature granulocytes and lymphocytes are negative. Applications Reported: This 10.1 antibody has been reported for use in flow cytometric analysis, and immunohistology staining of frozen tissue sections. Applications Tested: This 10.1 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay. Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC.

CD64 (FCGR1A) encodes a protein that plays an important role in the immune response. CD64 is a high-affinity Fc-gamma receptor and is one of three related gene family members located on chromosome 1. CD64 plays an important role in the immune response and its dysfunction has been studied in cervical adenitis and tetrasomy 21.
Specifications

Specifications

CD64 (Fc gamma Receptor 1)
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
Q92637, P12314
CD64, CD64A, FCRI, FLJ18345, IGFR1
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Control, Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen)
10.1
Functional Grade
FCGR1B
Liquid
FCGR1A, FCGR1B
IgG1, kappa
500 μg
4° C
Primary
2209, 2210
Documents

For Research Use Only.