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The P2H3 monoclonal antibody also inhibits cellular adhesion to cytokine-activated endothelial cells.Description & Specifications
DescriptionThe P2H3 monoclonal antibody reacts with human CD62E, a 97-115kDa member of the selectin family. CD62E, also known as E-selectin or endothelial-leukocyte adhesion molecule-1 (ELAM-1) is an adhesion molecule expressed by endothelial cells upon stimulation with cytokines including TNFα and IL-1β. Induced expression of CD62E during inflammatory conditions is thought to mediate leukocyte rolling including the initial interaction of neutrophils with endothelium.
The P2H3 monoclonal antibody also inhibits cellular adhesion to cytokine-activated endothelial cells.
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|