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CD59 (Protectin) Mouse anti-Human, FITC, Clone: OV9A2, eBioscience™

Mouse Monoclonal Antibody

$129.05 - $288.55

Specifications

Antigen CD59 (Protectin)
Clone OV9A2
Host Species Mouse
Gene Alias MIRL
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

509629

 
affymetrix
11059641
25 tests Each for $129.05

509630

 
affymetrix
11-0596-42
100 tests Each for $288.55
Description & Specifications

Specifications

Antigen CD59 (Protectin)
Clone OV9A2
Host Species Mouse
Gene Alias MIRL
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate FITC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.125μg)/test

This OV9A2 monoclonal antibody reacts with human CD59, which is also known as Protectin. This GPI-linked membrane glycoprotein shares structural homology with the murine Ly-6 superfamily. CD59 is expressed on all human lymphocytes, monocytes, granulocytes, and erythrocytes. This protein is also expressed on non-hematopoietic cells, including endothelial cells and neurons. By binding the complement components C8 and C9, CD59 inhibits assembly of the membrane attack complex and cytolytic activity by complement. CD59 interacts with CD2 to modulate T cell adhesion, and also plays a role in T cell activation. Finally, altered expression of CD55 and CD59 on human peripheral blood cells has been observed in patients with systemic lupus erythematosus (SLE).

Crossblocking studies indicate that the OV9A2 monoclonal antibody binds the same epitope as MEM-43.