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CD56 (NCAM) Mouse anti-Human, Non-human primate, Rhesus Monkey, eFluor® 450, Clone: TULY56, eBioscience™

Mouse Monoclonal Antibody

Manufacturer:  Life Technologies LS48056642

Catalog No. 501129760



Description

Description

Description: This TULY56 monoclonal antibody reacts with human CD56, also known as Neural Cell Adhesion Molecule (NCAM). CD56 is a highly glycosylated transmembrane molecule expressed by neurons and plays a role in the homotypic adhesion of neural cells.

2 μm post-manufacturing filtered. NCAM, as a member of the immunoglobulin superfamily of adhesion molecules is characterized by several immunoglobulin (Ig)-like domains. The extracellular part of NCAM consists of five of these Ig domains and two fibronectin type III homology regions. NCAM is encoded by a single copy gene composed of 26 exons. However, at least 20-30 distinct isoforms can be generated by alternative splicing and by posttranslational modifications, such as sialylation. During sialylation, polysialic acid (PSA) carbohydrates are attached to the extracellular part of NCAM. Through its extracellular region, NCAM mediates homophilic interactions. In addition, NCAM can also undergo heterophilic interactions by binding extracellular matrix components, such as laminin, or other cell adhesion molecules, such as integrins.
Specifications

Specifications

CD56 (NCAM)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P13591
NCAM1, NCAM, CD-56, MSK39, neural cell adhesion molecule 1
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human, Non-human primate, Rhesus Monkey
Flow Cytometry
TULY56
eFluor® 450
NCAM1
Liquid
NCAM1
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
4684, 693789
Documents

For Research Use Only.