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CD54 (ICAM-1) Rat anti-Mouse, Clone: KAT-1, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

$130.68 - $394.68

Specifications

Antigen CD54 (ICAM-1)
Clone KAT1)
Host Species Rat
Gene Alias Intercellular adhesion molecule-1
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5014349 Life Technologies
LS16054281
50μg Each for $130.68
5014351 Life Technologies
LS16054285
500μg Each for $394.68
Specifications

Description

The eBioKAT-1 monoclonal antibody reacts with mouse CD54 (ICAM-1), which is a 95kDa member of the immunoglobulin superfamily. CD54 is expressed at low levels on leukocytes and high endothelial venules, and expression increases in response to inflammatory cytokines. ICAM-1 binds to LFA-1 and this interaction is required for the transendothelial migration of T cells. ICAM-1-deficient mice are viable, however the migration of leukocytes to sites of inflammation is reduced leading to impaired immune and inflammatory responses. Based on the regulated expression of ICAM-1, it has been suggested that ICAM-1 may increase leukocyte extravasation at sites of inflammation, whereas the constitutively high expression of ICAM-2 mediates leukocyte traffic into non-inflamed tissue. The eBioKAT-1 monoclonal antibody recognizes a different epitope than the YN1/1.7.4 monoclonal antibody.
Description & Specifications

Specifications

CD54 (ICAM-1)
Rat
Mouse
RUO
Purified
Primary
aqueous buffer, no sodium azide
KAT1)
Intercellular adhesion molecule-1
Flow Cytometry,Functional Assay,Immunohistochemistry (Frozen),Immunoprecipitation
Unlabeled
Store at 2-8°C.
Monoclonal
1mg/mL