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Thermo Scientific™ Lab Vision™ CD54/ICAM-1 Ab-1, Mouse Monoclonal Antibody


Specifically detect human CD54 in immunohistochemistry and flow cytometry experiments with Thermo Scientific™ CD54/ICAM-1 Ab-1, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS114P1ABX

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Catalog No. MS114P1ABX

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Description & Specifications

Specifications

Antigen CD54/ICAM-1 Ab-1
Applications Flow Cytometry
Applications Immunohistochemistry
Classification Monoclonal
Clone 15.2
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Immunogen Human monocytes
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline Cell Adhesion
Type Primary

Specifically detect human CD54 in immunohistochemistry and flow cytometry experiments with Thermo Scientific™ CD54/ICAM-1 Ab-1, Mouse Monoclonal Antibody.

ICAM-1 (intercellular adhesion molecule) has 7 potential N-linked glycosylation sites. It is a single chain glycoprotein of Ig supergene family, present on unstimulated endo-thelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs.

Host Species: Mouse

Clone: 15.2

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Human monocytes

Molecular Weight: 85-115 kDa

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Acetone Fixed)
  • Flow Cytometry
  • Blocks binding of LFA-1 and infected RBCs to ICAM-3 (Order Ab without azide)

Note:

USA: RUO; Int'l: RUO