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Thermo Scientific™ Lab Vision™ CD54/ICAM-1 Ab-1, Mouse Monoclonal Antibody

Specifically detect human CD54 in immunohistochemistry and flow cytometry experiments with Thermo Scientific™ CD54/ICAM-1 Ab-1, Mouse Monoclonal Antibody.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS114P1ABX

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Catalog No. MS114P1ABX


 

Specifications

Description

Specifically detect human CD54 in immunohistochemistry and flow cytometry experiments with Thermo Scientific™ CD54/ICAM-1 Ab-1, Mouse Monoclonal Antibody.

ICAM-1 (intercellular adhesion molecule) has 7 potential N-linked glycosylation sites. It is a single chain glycoprotein of Ig supergene family, present on unstimulated endo-thelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs.

Host Species: Mouse

Clone: 15.2

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Human monocytes

Molecular Weight: 85-115 kDa

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Acetone Fixed)
  • Flow Cytometry
  • Blocks binding of LFA-1 and infected RBCs to ICAM-3 (Order Ab without azide)

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

CD54/ICAM-1 Ab-1
Monoclonal
1mg/mL
Human
Murine
IgG2a kappa
RUO
Primary
Human
Flow Cytometry,Immunohistochemistry
15.2
Unlabeled
Concentrated
Human monocytes
100μL
Cell Adhesion
Monoclonal