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CD49e (Integrin alpha 5) Armenian Hamster anti-Mouse, Rat, Clone: eBioHMa5-1 (HMa5-1), eBioscience™

Armenian Hamster Monoclonal Antibody

$129.05 - $361.05

Specifications

Antigen CD49e (Integrin alpha 5)
Clone eBioHMa5-1 (HMa5-1)
Host Species Armenian Hamster
Gene Alias Integrin a5, ITGA5, VLA5A
Species Reactivity Mouse, Rat
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Disclaimers:

For Research Use Only.



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Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5012629 Life Technologies
LS14049381
50μg Each for $129.05
5012630 Life Technologies
LS14049385
500μg Each for $361.05
Specifications

Description

The eBioHMα5-1 monoclonal antibody reacts with mouse and rat CD49e, also known as integrin α5 or VLA-5A. CD49e is a member of the integrin α chain family, and binds with CD29 (integrin β1) to form the receptor VLA-5, which binds the ligands fibronectin and fibrinogen. CD49e is a type I, single-pass membrane protein, with a molecular weight of 135 kDa, and is expressed on multiple cell types including thymocytes, mast cells, activated T cells and splenic B cells. In addition to its role in adhesion, VLA-5 contributes to T-cell co-stimulation. The eBioHMα5-1 monoclonal antibody has been demonstrated to interfere with VLA-5-mediated cell adhesion, and with the degranulation of IgE-sensitized rat RBL cells stimulated on fibronectin-coated plates. Furthermore, HMα5-1 injected into mice subcutaneously, along with anti-CD49d and anti-CD61, is able to inhibit passive cutaneous anaphylaxis.
Description & Specifications

Specifications

CD49e (Integrin alpha 5)
Armenian Hamster
Mouse, Rat
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
eBioHMa5-1 (HMa5-1)
Integrin a5, ITGA5, VLA5A
Flow Cytometry,Functional Assay,Immunoprecipitation
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL