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CD49e (Integrin alpha 5) Armenian Hamster anti-Mouse, Rat, Clone: eBioHMa5-1 (HMa5-1), eBioscience™

Armenian Hamster Monoclonal Antibody

$129.05 - $361.05

Specifications

Antigen CD49e (Integrin alpha 5)
Clone eBioHMa5-1 (HMa5-1)
Host Species Armenian Hamster
Gene Alias Integrin a5, ITGA5, VLA5A
Species Reactivity Mouse, Rat
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5012629

 
affymetrix
14-0493-81
50μg Each for $129.05

5012630

 
affymetrix
14-0493-85
500μg Each for $361.05
Description & Specifications

Specifications

Antigen CD49e (Integrin alpha 5)
Clone eBioHMa5-1 (HMa5-1)
Host Species Armenian Hamster
Gene Alias Integrin a5, ITGA5, VLA5A
Species Reactivity Mouse, Rat
Applications Flow Cytometry
Applications Functional Assay
Applications Immunoprecipitation
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The eBioHMα5-1 monoclonal antibody reacts with mouse and rat CD49e, also known as integrin α5 or VLA-5A. CD49e is a member of the integrin α chain family, and binds with CD29 (integrin β1) to form the receptor VLA-5, which binds the ligands fibronectin and fibrinogen. CD49e is a type I, single-pass membrane protein, with a molecular weight of 135 kDa, and is expressed on multiple cell types including thymocytes, mast cells, activated T cells and splenic B cells. In addition to its role in adhesion, VLA-5 contributes to T-cell co-stimulation. The eBioHMα5-1 monoclonal antibody has been demonstrated to interfere with VLA-5-mediated cell adhesion, and with the degranulation of IgE-sensitized rat RBL cells stimulated on fibronectin-coated plates. Furthermore, HMα5-1 injected into mice subcutaneously, along with anti-CD49d and anti-CD61, is able to inhibit passive cutaneous anaphylaxis.