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CD49d (Integrin alpha 4) Mouse anti-Rat, APC, Clone: MRa4-1, eBioscience™

Mouse Monoclonal Antibody

$143.55 - $361.05

Specifications

Antigen CD49d (Integrin alpha 4)
Clone MRa4-1
Host Species Mouse
Gene Alias ITGA4
Species Reactivity Rat
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123083

 
affymetrix
17149082
100μg Each for $361.05

501123082

 
affymetrix
17149080
25μg Each for $143.55
Description & Specifications

Specifications

Antigen CD49d (Integrin alpha 4)
Clone MRa4-1
Host Species Mouse
Gene Alias ITGA4
Species Reactivity Rat
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The MRa4-1 monoclonal antibody reacts with CD49d, which is also known as the integrin alpha 4 subunit. This 150kDa cell surface protein is expressed by thymocytes, peripheral lymphocytes, monocytes, and eosinophils in complex with either integrin beta1 or integrin beta7. Outside of the immune system, CD49d is also expressed on mast cells, neural crest cells, retinal cells, and dorsal root ganglion neurons. Integrins are responsible for lymphocyte homing to Peyer’s patches and mesenteric lymph nodes, as well as neural development and regeneration. Several ligands have been reported for the integrin a4b1 complex, including VCAM-1 (CD106) and fibronectin.

The MRa1-4 antibody has been reported to inhibit fibronectin binding and lymphocyte migration.