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CD49d (Integrin alpha 4) Mouse anti-Rat, APC, Clone: MRa4-1, eBioscience™

Mouse Monoclonal Antibody

$143.55 - $328.68

Specifications

Antigen CD49d (Integrin alpha 4)
Clone MRa4-1
Host Species Murine
Gene Alias ITGA4
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123083 Life Technologies
LS17149082
100μg Each for $328.68
501123082 Life Technologies
LS17149080
25μg Each for $143.55
Specifications

Description

The MRa4-1 monoclonal antibody reacts with CD49d, which is also known as the integrin alpha 4 subunit. This 150kDa cell surface protein is expressed by thymocytes, peripheral lymphocytes, monocytes, and eosinophils in complex with either integrin beta1 or integrin beta7. Outside of the immune system, CD49d is also expressed on mast cells, neural crest cells, retinal cells, and dorsal root ganglion neurons. Integrins are responsible for lymphocyte homing to Peyer’s patches and mesenteric lymph nodes, as well as neural development and regeneration. Several ligands have been reported for the integrin a4b1 complex, including VCAM-1 (CD106) and fibronectin.

The MRa1-4 antibody has been reported to inhibit fibronectin binding and lymphocyte migration.
Description & Specifications

Specifications

CD49d (Integrin alpha 4)
Murine
Flow Cytometry
Allophycocyanin
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL
MRa4-1
ITGA4
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer