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CD49c (Integrin alpha 3) Mouse anti-Human, APC, Clone: P1B5, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $390.05

Specifications

Antigen CD49c (Integrin alpha 3)
Clone P1B5
Host Species Mouse
Gene Alias VLA3, ITGA3
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014993

 
affymetrix
17-0494-41
25 tests Each for $187.05

5014994

 
affymetrix
17049442
100 tests Each for $390.05
Description & Specifications

Specifications

Antigen CD49c (Integrin alpha 3)
Clone P1B5
Host Species Mouse
Gene Alias VLA3, ITGA3
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.125μg)/test

This P1B5 monoclonal antibody reacts with human CD49c (also known as Integrin alpha 3). Integrins constitute a family of cell surface receptors that mediate adhesion between cells or between a cell and the extracellular matrix. These proteins are heterodimers consisting of two distinct subunits, α and β. Integrins are expressed on hematopoietic, non-hematopoietic, and cancer cells. Integrin-mediated adhesion is regulated by changes in ligand affinity (or activation), cell shape, and integrin clustering and diffusion. Integrin alpha 3 forms a complex with the common beta 1 subunit to form the α3β1 integrin. Studies have demonstrated the involvement of this integrin in wound healing and epithelial migration.

The P1B5 monoclonal antibody has been reported to affect adhesion to type I and VI collagens, as well as fibronectin and laminin.