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CD47 Mouse anti-Human, FITC, Clone: 2D3, eBioscience™

Mouse Monoclonal Antibody

$129.05 - $303.05

Specifications

Antigen CD47
Clone 2D3
Host Species Mouse
Gene Alias Integrin associated protein, IAP
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122069

 
affymetrix
11047841
25 tests Each for $129.05

501129192

 
affymetrix
11-0478-42
100 tests Each for $303.05
Description & Specifications

Specifications

Antigen CD47
Clone 2D3
Host Species Mouse
Gene Alias Integrin associated protein, IAP
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate FITC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (1μg)/test

The monoclonal antibody 2D3 reacts to CD47 also known as integrin-associated protein (IAP), and neurophilin. CD47 is a glycosylated five transmembrane protein with a small alternatively spliced cytoplasmic domain. CD47 is involved in adhesion through interactions with SIRP (signal regulator protein) and is non-covalently associated with β3 integrins CD51/CD61 and CD41/CD61. Furthermore this interaction can mediate bi-directional signaling to modify neural synaptic activity and regulate the phagocytic activities of macrophages. CD47 is the receptor for thrombospondin. T cell expression of CD47 can mediate activation or apoptosis (in the presence of high levels of thrombospondin). Expression is found in the majority of hematopoietic cells including T and B cells, monocytes, platelets and erythrocytes (as part of the Rh complex). Expression is also found in non-hematopoietic cells.