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Thermo Scientific™ Lab Vision™ CD47 Ab-2, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in immunofluorescence, immunoprecipitation and flow cytometry experiments with Thermo Scientific™ CD47 Ab-2, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1302PABX

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Catalog No. MS1302PABX

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Description & Specifications

Specifications

Antigen CD47 Ab-2
Applications Immunofluorescence
Applications Immunoprecipitation
Applications Western Blotting
Classification Monoclonal
Clone B6H12.2
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Immunogen Intact CD47 purified from placenta
Isotype IgG2a kappa
Quantity 200µL
Regulatory Status RUO
Research Discipline Hematopoietic
Type Primary

Ensure accurate, reproducible results in immunofluorescence, immunoprecipitation and flow cytometry experiments with Thermo Scientific™ CD47 Ab-2, Mouse Monoclonal Antibody.

CD47 antigen, also known as integrin associated-protein (IAP), is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 may play a role as a signal transducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells.

Host Species: Mouse

Clone: B6H12.2

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Ig domain

Immunogen: Intact CD47 purified from placenta

Molecular Weight: 47-52 kDa (reduced) and 45-50.5, 110 kDa (nonreduced)

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunofluorescence (Methanol fixed only)
  • Immunoprecipitation (Native only)
  • Flow Cytometry
  • Blocks binding of SIRPα
  • Inhibits in assays in which CD47-integrin association is required

Note:

USA: RUO; Int'l: RUO