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CD43 Rat anti-Mouse, Clone: eBioR2/60, eBioscience™

Rat Monoclonal Antibody

$77.88 - $315.48

Specifications

Antigen CD43
Clone eBioR2/60
Host Species Rat
Gene Alias Leukosialin, LSN, Sialophorin, SPN
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5012575 Life Technologies
LS14043181
50μg Each for $77.88
5012576 Life Technologies
LS14043182
100μg Each for $143.88
5012577 Life Technologies
LS14043185
500μg Each for $315.48
Specifications

Description

The eBioR2/60 monoclonal antibody reacts with mouse CD43, also known as leukosialin and sialophorin. CD43 has glycoforms of approximately 115 and 130 kDa, and is expressed by an early B cell subset in BM, thymocytes and mature T cells, NK cells, myeloid lineage cells and platelets. CD43 is reported to bind to CD54 and play a role in adhesion and B cell survival.

While the S7 and 1B11 monoclonal antibody clones detect only certain isoforms of CD43, data suggests that R2/60 detects the expression of both isoforms. It has been demonstrated that R2/60 stains the majority of CD4+ and CD8+ splenocytes, as well as a significant population of CD19+ splenocytes. However, the clones S7 and 1B11 stain only CD4+ and CD8+, or CD19+ splenocytes, respectively. This suggests that S7 and 1B11 recognize distinct epitopes which are differentially expressed by splenic B and T cells, whereas R2/60 recognizes an epitope shared by both isoforms of CD43.
Description & Specifications

Specifications

CD43
Rat
Mouse
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
eBioR2/60
Leukosialin, LSN, Sialophorin, SPN
Flow Cytometry,Immunoprecipitation,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL