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CD42a Mouse anti-Human, eFluor 450, Clone: GR-P, eBioscience™

Mouse Monoclonal Antibody

$143.55 - $317.55

Specifications

Antigen CD42a
Clone GR-P
Host Species Mouse
Gene Alias Glycoprotein IX, GP9
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

50245992

 
affymetrix
48042841
25 tests Each for $143.55

50245993

 
affymetrix
48042842
100 tests Each for $317.55
Description & Specifications

Specifications

Antigen CD42a
Clone GR-P
Host Species Mouse
Gene Alias Glycoprotein IX, GP9
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate eFluor 450
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

This GR-P monoclonal antibody reacts with human CD42a, which is also known as glycoprotein IX (GPIX). CD42a is a 22kDa transmembrane protein that is constitutively expressed on platelets and megakaryocytes. CD42a associates with CD42b, CD42c, and CD42d to form the GPIb-V-IX complex, which binds the von Willebrand factor, an endothelial adhesion protein, to mediate platelet adhesion and activation. This binding results in platelet aggregation at sites of vascular injury. This receptor complex has also been demonstrated to bind thrombin, factors XI and XII, P-selectin, and Mac-1. Finally, a point mutation within the leucine-rich motif of CD42a has been linked to Bernard-Soulier syndrome.