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CD42a Mouse anti-Human, eFluor 450, Clone: GR-P, eBioscience™

Mouse Monoclonal Antibody

$158.05 - $324.80

Specifications

Antigen CD42a
Clone GR-P
Host Species Murine
Gene Alias Glycoprotein IX, GP9
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
50245992 Life Technologies
LS48042841
25 Tests Each for $158.05
50245993 Life Technologies
LS48042842
100 Tests Each for $324.80
Specifications

Description

This GR-P monoclonal antibody reacts with human CD42a, which is also known as glycoprotein IX (GPIX). CD42a is a 22kDa transmembrane protein that is constitutively expressed on platelets and megakaryocytes. CD42a associates with CD42b, CD42c, and CD42d to form the GPIb-V-IX complex, which binds the von Willebrand factor, an endothelial adhesion protein, to mediate platelet adhesion and activation. This binding results in platelet aggregation at sites of vascular injury. This receptor complex has also been demonstrated to bind thrombin, factors XI and XII, P-selectin, and Mac-1. Finally, a point mutation within the leucine-rich motif of CD42a has been linked to Bernard-Soulier syndrome.
Description & Specifications

Specifications

CD42a
Murine
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
GR-P
Glycoprotein IX, GP9
Flow Cytometry
eFluor 450
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.25μg)/test