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CD40 Rat anti-Mouse, Clone: 1C10, eBioscience™

Rat Monoclonal Antibody

$91.08 - $592.68

Specifications

Antigen CD40
Clone 1C10
Host Species Rat
Gene Alias TNFRSF5
Applications Flow Cytometry,Immunohistochemistry (Frozen),Immunoprecipitation
View More Specs

Disclaimers:

For Research Use Only.



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Specifications

Description

The 1C10 monoclonal antibody reacts with mouse CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.

The monoclonal antibody 1C10 is reported to have agonistic activity in vitro and in vivo.
Description & Specifications

Specifications

CD40
Rat
Flow Cytometry,Immunohistochemistry (Frozen),Immunoprecipitation
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL
1C10
TNFRSF5
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer