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CD40 Rat anti-Mouse, Clone: 1C10, eBioscience™

Rat Monoclonal Antibody

$100.05 - $651.05

Specifications

Antigen CD40
Clone 1C10
Host Species Rat
Gene Alias TNFRSF5
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



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Catalog Number Mfr. No. Quantity Price Quantity  
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5012556 Life Technologies
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Specifications

Description

The 1C10 monoclonal antibody reacts with mouse CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.

The monoclonal antibody 1C10 is reported to have agonistic activity in vitro and in vivo.
Description & Specifications

Specifications

CD40
Rat
Mouse
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
1C10
TNFRSF5
Flow Cytometry,Immunohistochemistry (Frozen),Immunoprecipitation
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL