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CD40 Rat anti-Mouse, Biotin, Clone: 1C10, eBioscience™

Rat Monoclonal Antibody

$143.55 - $709.05

Specifications

Antigen CD40
Clone 1C10
Host Species Rat
Gene Alias TNFRSF5
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5011528

 
affymetrix
13-0401-81
50μg Each for $143.55

5011529

 
affymetrix
13-0401-82
100μg Each for $274.05

5011531

 
affymetrix
13-0401-86
1mg Each for $709.05

5011530

 
affymetrix
13-0401-85
500μg Each for $390.05
Description & Specifications

Specifications

Antigen CD40
Clone 1C10
Host Species Rat
Gene Alias TNFRSF5
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Biotin
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The 1C10 monoclonal antibody reacts with mouse CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.

The monoclonal antibody 1C10 is reported to have agonistic activity in vitro and in vivo.