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CD40 Mouse anti-Human, eFluor 450, Clone: 5C3, eBioscience™

Mouse Monoclonal Antibody

$143.88 - $368.28

Specifications

Antigen CD40
Clone 5C3
Host Species Murine
Gene Alias TNFRSF5
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
50245990 Life Technologies
LS48040941
25 Tests Each for $143.88
50245991 Life Technologies
LS48040942
100 Tests Each for $368.28
Specifications

Description

The 5C3 monoclonal antibody reacts with human CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development and maturation by inducing Ig isotype-switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation. 5C3 is reported to be used for activation of B cells in in vitro functional assays.
Description & Specifications

Specifications

CD40
Murine
Flow Cytometry
eFluor 450
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.125μg)/test
5C3
TNFRSF5
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer