Please login to your online account to display your discounted pricing

CD40 Mouse anti-Human, Clone: 5C3, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

$158.05 - $477.05

Specifications

Antigen CD40
Clone 5C3
Host Species Mouse
Gene Alias TNFRSF5
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014307

 
affymetrix
16040981
50μg Each for $158.05

501129447

 
affymetrix
16-0409-85
500μg Each for $477.05
Description & Specifications

Specifications

Antigen CD40
Clone 5C3
Host Species Mouse
Gene Alias TNFRSF5
Species Reactivity Human
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The 5C3 monoclonal antibody reacts with human CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development and maturation by inducing Ig isotype-switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation. 5C3 is reported to be used for activation of B cells in in vitro functional assays.