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CD40 Mouse anti-Human, Clone: 5C3, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

$143.88 - $434.28

Specifications

Antigen CD40
Clone 5C3
Host Species Murine
Gene Alias TNFRSF5
Applications Flow Cytometry,Functional Assay
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5014307 Life Technologies
LS16040981
50μg Each for $143.88
501129447 Life Technologies
LS16040985
500μg Each for $434.28
Specifications

Description

The 5C3 monoclonal antibody reacts with human CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development and maturation by inducing Ig isotype-switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation. 5C3 is reported to be used for activation of B cells in in vitro functional assays.
Description & Specifications

Specifications

CD40
Murine
Flow Cytometry,Functional Assay
Unlabeled
Store at 2-8°C.
Monoclonal
1mg/mL
5C3
TNFRSF5
RUO
Purified
Primary
aqueous buffer, no sodium azide