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CD40 Armenian Hamster anti-Mouse, Rat, eFluor 450, Clone: HM40-3, eBioscience™

Armenian Hamster Monoclonal Antibody

$187.05 - $375.55

Specifications

Antigen CD40
Clone HM40-3
Host Species Armenian Hamster
Gene Alias TNFRSF5
Species Reactivity Mouse, Rat
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501124111

 
affymetrix
48040282
100μg Each for $375.55

501129283

 
affymetrix
48-0402-80
25μg Each for $187.05
Description & Specifications

Specifications

Antigen CD40
Clone HM40-3
Host Species Armenian Hamster
Gene Alias TNFRSF5
Species Reactivity Mouse, Rat
Applications Flow Cytometry
Regulatory Status RUO
Conjugate eFluor 450
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The HM40-3 monoclonal antibody reacts with mouse and rat CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.