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CD40 Armenian Hamster anti-Mouse, Rat, Clone: HM40-3, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody, Functional Grade

$143.55 - $752.55

Specifications

Antigen CD40
Clone HM40-3
Host Species Armenian Hamster
Gene Alias TNFRSF5
Species Reactivity Mouse, Rat
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014303

 
affymetrix
16-0402-81
50μg Each for $143.55

5014304

 
affymetrix
16040282
100μg Each for $245.05

5014306

 
affymetrix
16040286
1mg Each for $752.55

501129550

 
affymetrix
16-0402-85
500μg Each for $404.55
Description & Specifications

Specifications

Antigen CD40
Clone HM40-3
Host Species Armenian Hamster
Gene Alias TNFRSF5
Species Reactivity Mouse, Rat
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The HM40-3 monoclonal antibody reacts with mouse and rat CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.