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CD40 Armenian Hamster anti-Mouse, Rat, Clone: HM40-3, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody, Functional Grade

$143.55 - $752.55

Specifications

Antigen CD40
Clone HM40-3
Host Species Armenian Hamster
Gene Alias TNFRSF5
Species Reactivity Mouse, Rat
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014303

 
life technologies
LS16040281
50μg Each for $143.55

5014304

 
life technologies
LS16040282
100μg Each for $245.05

5014306

 
life technologies
LS16040286
1mg Each for $752.55

501129550

 
life technologies
LS16040285
500μg Each for $404.55
Description & Specifications

Specifications

Antigen CD40
Clone HM40-3
Host Species Armenian Hamster
Gene Alias TNFRSF5
Species Reactivity Mouse, Rat
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The HM40-3 monoclonal antibody reacts with mouse and rat CD40, a 45-50kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.