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CD39 Rat anti-Mouse, Clone: 24DMS1, eBioscience™

Rat Monoclonal Antibody

$129.05 - $303.05

Specifications

Antigen CD39
Clone 24DMS1
Host Species Rat
Gene Alias Ectonucleoside Triphosphate Diphosphohydrolase 1, Entpd1
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5012549

 
affymetrix
14-0391-80
25μg Each for $129.05

5012550

 
affymetrix
14039182
100μg Each for $303.05
Description & Specifications

Specifications

Antigen CD39
Clone 24DMS1
Host Species Rat
Gene Alias Ectonucleoside Triphosphate Diphosphohydrolase 1, Entpd1
Species Reactivity Mouse
Applications Flow Cytometry
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The 24DMS1 monoclonal antibody reacts with mouse CD39, also known as NTPDaseI. E-NTPDases are enzymes that convert nucleoside tri- and diphosphates (NTDPs) into nucleoside monophosphate (NMP), thereby removing toxic extracellular ATP and ADP. CD39 is the dominant member of this family in the immune system and is involved in suppression of inflammation and control of platelet activation. CD39 can impact expression of CD73, another E-NTPase. Together, these molecules influence inflammation responses. CD39 is expressed on B cells, Langerhans cells and most monocytes. In addition, CD39 is found on a subset of CD4+ T cells that are mostly CD25+FoxP3+ T reg cells. T reg cells from CD39-null mice showed impaired suppressive properties in vitro and in vivo.