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CD39 Mouse anti-Human, Clone: eBioA1 (A1), eBioscience™

Mouse Monoclonal Antibody

$129.05 - $303.05

Specifications

Antigen CD39
Clone eBioA1 (A1)
Host Species Mouse
Gene Alias Ectonucleoside Triphosphate Diphosphohydrolase 1, Entpd1
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5012551

 
affymetrix
14039980
25μg Each for $129.05

5012552

 
affymetrix
14039982
100μg Each for $303.05
Description & Specifications

Specifications

Antigen CD39
Clone eBioA1 (A1)
Host Species Mouse
Gene Alias Ectonucleoside Triphosphate Diphosphohydrolase 1, Entpd1
Species Reactivity Human
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The eBioA1 monoclonal antibody reacts with human CD39 also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) or NTPDase. CD39 is an integral membrane protein with two transmembrane domains and exists as a homotetramer. It is the most prominent ectoenzyme of the immune system. The function of CD39 is to effectively remove toxic extracellular ATP by converting it to ADP or AMP. CD39 is thought to work together with CD73 to hydrolyze ATP and has been well characterized on Langerhans cells. Expression of CD39 was originally identified on activated lymphocytes. Expression is also found on a subset of T cells, B cells and dendritic cells as well as weak staining on monocytes and granulocytes.

Recently, CD39 and CD73 have been found on regulatory T cells (Treg). Expression of CD39 on Treg may facilitate their entry into inflamed areas where high levels of ATP are present. Expression of CD39 on Foxp3+CD4+ cells ranges from 25-45%.