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CD39 Mouse anti-Human, APC, Clone: A1, eBioscience™

Mouse Monoclonal Antibody

$174.24 - $376.20

Specifications

Antigen CD39
Clone eBioA1 (A1)
Host Species Murine
Gene Alias Ectonucleoside Triphosphate Diphosphohydrolase 1, Entpd1
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5014957 Life Technologies
LS17039941
25 Tests Each for $174.24
5014958 Life Technologies
LS17039942
100 Tests Each for $376.20
Specifications

Description

The eBioA1 monoclonal antibody reacts with human CD39 also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) or NTPDase. CD39 is an integral membrane protein with two transmembrane domains and exists as a homotetramer. It is the most prominent ectoenzyme of the immune system. The function of CD39 is to effectively remove toxic extracellular ATP by converting it to ADP or AMP. CD39 is thought to work together with CD73 to hydrolyze ATP and has been well characterized on Langerhans cells. Expression of CD39 was originally identified on activated lymphocytes. Expression is also found on a subset of T cells, B cells and dendritic cells as well as weak staining on monocytes and granulocytes.

Recently, CD39 and CD73 have been found on regulatory T cells (Treg). Expression of CD39 on Treg may facilitate their entry into inflamed areas where high levels of ATP are present. Expression of CD39 on Foxp3+CD4+ cells ranges from 25-45%.
Description & Specifications

Specifications

CD39
Murine
Flow Cytometry
Allophycocyanin
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.125μg)/test
eBioA1 (A1)
Ectonucleoside Triphosphate Diphosphohydrolase 1, Entpd1
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer