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CD38 Rat anti-Mouse, PE-Cy7, Clone: 90, eBioscience™

Rat Monoclonal Antibody

$158.05 - $419.05

Specifications

Antigen CD38
Clone 90
Host Species Rat
Gene Alias ADP-Ribosyl Cyclase, Cyclic ADP-Ribose Hydrolase
Species Reactivity Mouse
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123285

 
affymetrix
25038182
100μg Each for $419.05

501123284

 
affymetrix
25038180
25μg Each for $158.05
Description & Specifications

Specifications

Antigen CD38
Clone 90
Host Species Rat
Gene Alias ADP-Ribosyl Cyclase, Cyclic ADP-Ribose Hydrolase
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE-Cy7
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The 90 monoclonal antibody reacts with the mouse CD38 molecule, an ∽42kDa type II transmembrane protein. CD38 is expressed at increasingly higher levels on B cells at each stage of B-cell differentiation, and is then down-regulated on germinal center B cells and mature plasma cells. Its expression is reported on a subpopulation of thymocytes, mature T cells, and NK cells. Crosslinking of CD38 on the surface of mature, resting B cells induces B-cell proliferation, which is enhanced by co-signals such as IL-4 and LPS. CD38, a counter-receptor for CD31, is an ectoenzyme with cyclase and hydrolase enzymatic activity and is speculated to play a role in lymphocyte activation and differentiation.