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CD38 Rat anti-Mouse, FITC, Clone: 90, eBioscience™

Rat Monoclonal Antibody

$129.05 - $230.55

Specifications

Antigen CD38
Clone 90
Host Species Rat
Gene Alias ADP-Ribosyl Cyclase, Cyclic ADP-Ribose Hydrolase
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

509538

 
affymetrix
11038181
50μg Each for $129.05

509539

 
affymetrix
11-0381-82
100μg Each for $230.55
Description & Specifications

Specifications

Antigen CD38
Clone 90
Host Species Rat
Gene Alias ADP-Ribosyl Cyclase, Cyclic ADP-Ribose Hydrolase
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate FITC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The 90 monoclonal antibody reacts with the mouse CD38 molecule, an ∽42kDa type II transmembrane protein. CD38 is expressed at increasingly higher levels on B cells at each stage of B-cell differentiation, and is then down-regulated on germinal center B cells and mature plasma cells. Its expression is reported on a subpopulation of thymocytes, mature T cells, and NK cells. Crosslinking of CD38 on the surface of mature, resting B cells induces B-cell proliferation, which is enhanced by co-signals such as IL-4 and LPS. CD38, a counter-receptor for CD31, is an ectoenzyme with cyclase and hydrolase enzymatic activity and is speculated to play a role in lymphocyte activation and differentiation.