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CD38 Mouse anti-Human, PE-Cy7, Clone: HB7, eBioscience™

Mouse Monoclonal Antibody

$169.65 - $427.75

Specifications

Antigen CD38
Clone HB7
Host Species Murine
Gene Alias ADP-Ribosyl Cyclase, Cyclic ADP-Ribose Hydrolase
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123286 Life Technologies
LS25038841
25 Tests Each for $169.65
501123287 Life Technologies
LS25038842
100 Tests Each for $427.75
Specifications

Description

The HB7 monoclonal antibody reacts with the human CD38 molecule, an approximately 45kDa type II transmembrane protein. CD38 is an ectoenzyme which catalyses NAD into nicotinic acid adenine dinucleotide phosphate (NAADP) and cyclic ADP-ribose (cADPR), both of which are secondary messengers. Expression of CD38 is bimodal during B cell development, modulating from high in immature cells to low in intermediate ones and back to high on mature B cells. Additionally CD38 is found in a variety of tissues and other hematopoietic cells (e.g. T cells, NK cells and monocytes) and can be used to phenotype leukemias and monitor HIV-1 progression. The CD34+CD38- population of hematopoietic stems cells is thought to define the most pluripotent cells (e.g. blast colony forming cells). In addition to surface expression, CD38 has recently been found in the nucleus where it may play a role in monitoring calcium levels.
Description & Specifications

Specifications

CD38
Murine
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
HB7
ADP-Ribosyl Cyclase, Cyclic ADP-Ribose Hydrolase
Flow Cytometry
PE-Cy7
Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Monoclonal
5μL (0.125μg)/test