Please login to your online account to display your discounted pricing

CD38 Mouse anti-Human, eFluor 450, Clone: HB7, eBioscience™

Mouse Monoclonal Antibody

$143.55 - $332.05

Specifications

Antigen CD38
Clone HB7
Host Species Mouse
Gene Alias ADP-Ribosyl Cyclase, Cyclic ADP-Ribose Hydrolase
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

50245988

 
affymetrix
48038841
25 tests Each for $143.55

50245989

 
affymetrix
48038842
100 tests Each for $332.05
Description & Specifications

Specifications

Antigen CD38
Clone HB7
Host Species Mouse
Gene Alias ADP-Ribosyl Cyclase, Cyclic ADP-Ribose Hydrolase
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate eFluor 450
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.06μg)/test

The HB7 monoclonal antibody reacts with the human CD38 molecule, an approximately 45kDa type II transmembrane protein. CD38 is an ectoenzyme which catalyses NAD into nicotinic acid adenine dinucleotide phosphate (NAADP) and cyclic ADP-ribose (cADPR), both of which are secondary messengers. Expression of CD38 is bimodal during B cell development, modulating from high in immature cells to low in intermediate ones and back to high on mature B cells. Additionally CD38 is found in a variety of tissues and other hematopoietic cells (e.g. T cells, NK cells and monocytes) and can be used to phenotype leukemias and monitor HIV-1 progression. The CD34+CD38- population of hematopoietic stems cells is thought to define the most pluripotent cells (e.g. blast colony forming cells). In addition to surface expression, CD38 has recently been found in the nucleus where it may play a role in monitoring calcium levels.