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CD370 (Clec9A) Rat anti-Mouse, PerCP-eFluor 710, Clone: 42D2, eBioscience™

Rat Monoclonal Antibody

$187.05 - $448.05

Specifications

Antigen CD370 (Clec9A)
Clone 42D2
Host Species Rat
Gene Alias DNGR-1
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5016091 Life Technologies
LS46597580
25μg Each for $187.05
5016092 Life Technologies
LS46597582
100μg Each for $448.05
Specifications

Description

This 42D2 monoclonal antibody reacts with mouse CD370, which is also known as DNGR-1 or Clec9A. CD370 is a C-type lectin-like receptor expressed on conventional and plasmacytoid dendritic cells (DCs). In particular, CD8+ conventional DCs in the thymus, spleen, and lymph nodes, as well as CD24+ DCs in the blood, express CD370. This receptor is not detectable on most B cells, T and NK cells, monocytes, and macrophages. The cytoplasmic domain of CD370 contains an ITAM motif that has been demonstrated to phosphorylate Syk tyrosine kinase, leading to NFAT activation. This signaling reportedly mediates the presentation of necrotic cell-associated antigens by CD8+ DCs in innate immunity.
Description & Specifications

Specifications

CD370 (Clec9A)
Rat
Mouse
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
42D2
DNGR-1
Flow Cytometry
PerCP-eFluor 710
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL