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CD370 (Clec9A) Rat anti-Mouse, PE, Clone: 42D2, eBioscience™

Rat Monoclonal Antibody

$130.68 - $368.28

Specifications

Antigen CD370 (Clec9A)
Clone 42D2
Host Species Rat
Gene Alias DNGR-1
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5011043 Life Technologies
LS12597580
25μg Each for $130.68
5011044 Life Technologies
LS12597582
100μg Each for $368.28
Specifications

Description

This 42D2 monoclonal antibody reacts with mouse CD370, which is also known as DNGR-1 or Clec9A. CD370 is a C-type lectin-like receptor expressed on conventional and plasmacytoid dendritic cells (DCs). In particular, CD8+ conventional DCs in the thymus, spleen, and lymph nodes, as well as CD24+ DCs in the blood, express CD370. This receptor is not detectable on most B cells, T and NK cells, monocytes, and macrophages. The cytoplasmic domain of CD370 contains an ITAM motif that has been demonstrated to phosphorylate Syk tyrosine kinase, leading to NFAT activation. This signaling reportedly mediates the presentation of necrotic cell-associated antigens by CD8+ DCs in innate immunity.
Description & Specifications

Specifications

CD370 (Clec9A)
Rat
Flow Cytometry
PE
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL
42D2
DNGR-1
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer