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CD369 (Clec7A, Dectin-1) Mouse anti-Human, Non-human primate, PerCP-eFluor 710, Clone: 15E2, eBioscience™

Mouse Monoclonal Antibody

$201.55 - $506.05

Specifications

Antigen CD369 (Clec7A, Dectin-1)
Clone 1.50E+03
Host Species Mouse
Gene Alias Beta-glucan receptor, ClecSF12
Species Reactivity Human, Non-human primate
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123973

 
affymetrix
46985641
25 tests Each for $201.55

501123974

 
affymetrix
46985642
100 tests Each for $506.05
Description & Specifications

Specifications

Antigen CD369 (Clec7A, Dectin-1)
Clone 1.50E+03
Host Species Mouse
Gene Alias Beta-glucan receptor, ClecSF12
Species Reactivity Human, Non-human primate
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PerCP-eFluor 710
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

This 15E2 monoclonal antibody reacts with human and non-human primate CD369, which is also known as the Dectin-1 or beta-glucan receptor or CLEC7A. CD369 is expressed predominantly on monocytes, macrophages, and dendritic cells. Moreover, this receptor can also be detected on neutrophils and lymphocytes, as well as induced by cytokines such as IL-4 or LPS. In humans, CD369 exists as two isoforms that arise due to alternative splicing. CD369 binds beta-1,3-glucan and plays an important role in activating signal transduction involved in the innate immune response to fungal and mycobacterial infections. Studies have also shown the involvement of CD369 in dendritic cell activation.

The 15E2 monoclonal antibody has been reported to recognize both isoforms of CD369 and activate dendritic cells. It does not crossreact to mouse CD369.