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CD369 (Clec7A, Dectin-1) Mouse anti-Human, Non-human primate, PerCP-eFluor 710, Clone: 15E2, eBioscience™

Mouse Monoclonal Antibody

$201.55 - $506.05

Specifications

Antigen CD369 (Clec7A, Dectin-1)
Clone 1.50E+03
Host Species Murine
Gene Alias Beta-glucan receptor, ClecSF12
Species Reactivity Human, Non-human primate
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123973 Life Technologies
LS46985641
25 Tests Each for $201.55
501123974 Life Technologies
LS46985642
100 Tests Each for $506.05
Specifications

Description

This 15E2 monoclonal antibody reacts with human and non-human primate CD369, which is also known as the Dectin-1 or beta-glucan receptor or CLEC7A. CD369 is expressed predominantly on monocytes, macrophages, and dendritic cells. Moreover, this receptor can also be detected on neutrophils and lymphocytes, as well as induced by cytokines such as IL-4 or LPS. In humans, CD369 exists as two isoforms that arise due to alternative splicing. CD369 binds beta-1,3-glucan and plays an important role in activating signal transduction involved in the innate immune response to fungal and mycobacterial infections. Studies have also shown the involvement of CD369 in dendritic cell activation.

The 15E2 monoclonal antibody has been reported to recognize both isoforms of CD369 and activate dendritic cells. It does not crossreact to mouse CD369.
Description & Specifications

Specifications

CD369 (Clec7A, Dectin-1)
Murine
Human, Non-human primate
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
1.50E+03
Beta-glucan receptor, ClecSF12
Flow Cytometry
PerCP-eFluor 710
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.25μg)/test