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CD369 (Clec7A, Dectin-1) Mouse anti-Human, Non-human primate, Clone: 15E2, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

$249.48 - $421.08

Specifications

Antigen CD369 (Clec7A, Dectin-1)
Clone 1.50E+03
Host Species Murine
Gene Alias Beta-glucan receptor, CLEC7A
Applications Functional Assay
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123011 Life Technologies
LS16985682
100μg Each for $249.48
501123012 Life Technologies
LS16985685
500μg Each for $421.08
Specifications

Description

This 15E2 monoclonal antibody reacts with human and non-human primate CD369, which is also known as the Dectin-1 or beta-glucan receptor or CLEC7A. CD369 is expressed predominantly on monocytes, macrophages, and dendritic cells. Moreover, this receptor can also be detected on neutrophils and lymphocytes, as well as induced by cytokines such as IL-4 or LPS. In humans, CD369 exists as two isoforms that arise due to alternative splicing. CD369 binds beta-1,3-glucan and plays an important role in activating signal transduction involved in the innate immune response to fungal and mycobacterial infections. Studies have also shown the involvement of CD369 in dendritic cell activation.

The 15E2 monoclonal antibody has been reported to recognize both isoforms of CD369 and activate dendritic cells. It does not crossreact to mouse CD369.
Description & Specifications

Specifications

CD369 (Clec7A, Dectin-1)
Murine
Functional Assay
Unlabeled
Store at 2-8°C.
Monoclonal
1mg/mL
1.50E+03
Beta-glucan receptor, CLEC7A
RUO
Purified
Primary
aqueous buffer, no sodium azide