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CD365 (TIM1) Rat anti-Mouse, Biotin, Clone: RMT1-4, eBioscience™

Rat Monoclonal Antibody

$158.05 - $506.05

Specifications

Antigen CD365 (TIM1)
Clone RMT1-4
Host Species Rat
Gene Alias HAVCR1, T cell immunoglobulin and mucin domain-containing protein 1
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122559

 
affymetrix
13586182
100μg Each for $303.05

5011948

 
affymetrix
13586181
50μg Each for $158.05

5011950

 
affymetrix
13586185
500μg Each for $506.05
Description & Specifications

Specifications

Antigen CD365 (TIM1)
Clone RMT1-4
Host Species Rat
Gene Alias HAVCR1, T cell immunoglobulin and mucin domain-containing protein 1
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Biotin
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The RMT1-4 monoclonal antibody reacts with mouse CD365 (also known as TIM1 and HAVCR1) and is a member of the T cell immunoglobulin domain, mucin-like domain (TIM) gene family. CD365 has been found on activated CD4+ T cells, mast cells, and a subset of B cells. CD365 is involved in renal injury, tissue homeostasis, and T cell costimulation. CD365 promotes the differentiation of Th2 cells and the production of IL-4. CD365 can bind several ligands, including Hepatitis A virus, phosphatidylserine, TIM4, IgA, as well as itself. CD365 and TIM4 can mediate uptake of apoptotic cells through recognition of phosphatidylserine. CD365, as well as the other TIM family members, are associated with susceptibility to atopic and autoimmune diseases. In humans, certain polymorphic variants of CD365 are strongly associated with protection against atopy, and this association occurs only in individuals who have had past infection with hepatitis A virus (HAV).