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CD365 (TIM1) Rat anti-Mouse, Biotin, Clone: RMT1-4, eBioscience™

Rat Monoclonal Antibody

$143.88 - $460.68

Specifications

Antigen CD365 (TIM1)
Clone RMT1-4
Host Species Rat
Gene Alias HAVCR1, T cell immunoglobulin and mucin domain-containing protein 1
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122559 Life Technologies
LS13586182
100μg Each for $275.88
5011948 Life Technologies
LS13586181
50μg Each for $143.88
5011950 Life Technologies
LS13586185
500μg Each for $460.68
Specifications

Description

The RMT1-4 monoclonal antibody reacts with mouse CD365 (also known as TIM1 and HAVCR1) and is a member of the T cell immunoglobulin domain, mucin-like domain (TIM) gene family. CD365 has been found on activated CD4+ T cells, mast cells, and a subset of B cells. CD365 is involved in renal injury, tissue homeostasis, and T cell costimulation. CD365 promotes the differentiation of Th2 cells and the production of IL-4. CD365 can bind several ligands, including Hepatitis A virus, phosphatidylserine, TIM4, IgA, as well as itself. CD365 and TIM4 can mediate uptake of apoptotic cells through recognition of phosphatidylserine. CD365, as well as the other TIM family members, are associated with susceptibility to atopic and autoimmune diseases. In humans, certain polymorphic variants of CD365 are strongly associated with protection against atopy, and this association occurs only in individuals who have had past infection with hepatitis A virus (HAV).
Description & Specifications

Specifications

CD365 (TIM1)
Rat
Flow Cytometry
Biotin
Store at 2-8°C. Do not freeze.
Monoclonal
0.5mg/mL
RMT1-4
HAVCR1, T cell immunoglobulin and mucin domain-containing protein 1
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer