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CD36 Mouse anti-Human, Clone: eBioNL07 (NL07), eBioscience™

Mouse Monoclonal Antibody

$85.55 - $216.05

Specifications

Antigen CD36
Clone eBioNL07 (NL07)
Host Species Mouse
Gene Alias GP IIIb, Thrombospondin Receptor
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5012540

 
affymetrix
14-0369-80
25μg Each for $85.55

5012541

 
affymetrix
14-0369-82
100μg Each for $216.05
Description & Specifications

Specifications

Antigen CD36
Clone eBioNL07 (NL07)
Host Species Mouse
Gene Alias GP IIIb, Thrombospondin Receptor
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The monoclonal antibody eBioNL07 recognizes human CD36, which is a member of the class B scavenger receptor family. CD36 was originally identified as a platelet-membrane glycoprotein also called glycoprotein IV and a receptor for thrombospondin-1 (TSP-1) and extracellular matrix proteins. Binding to TSP-1 is in the CLESH (CD36 LIMP-II Emp sequence homology) domain of CD36. CD36 expression is broad and includes microvascular (but not large vessel) endothelium, adipocytes, skeletal muscle, dendritic cells, epithelia of the retina, breast, and intestine, smooth muscle cells, and hematopoietic cells, including erythroid precursors, platelets, monocytes/macrophages, DCs and megakaryocytes. Expression on platelets is absent on Naka negative donors. Unlike other scavenger receptor, CD36 binds LDL that has been exposed to “minimally” oxidizing conditions. CD36 is also a fatty acid translocase (FAT) necessary for the transport of long-chain fatty acids (LCFAs) and therefore may play a role in atherosclerosis.