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Thermo Scientific™ Lab Vision™ CD36/GPIIIb/GPIV Ab-3, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry , immunofluorescence, flow cytometry and function blocking experiment.

Manufacturer: thermo scientific™ lab vision™  MS756P1ABX

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Catalog No. MS756P1ABX

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Description & Specifications

Specifications

Antigen CD36/GPIIIb/GPIV Ab-3
Applications Flow Cytometry
Applications Immunofluorescence
Applications Immunohistochemistry (Frozen)
Classification Monoclonal
Clone 185-1G2
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Immunogen Stimulated human leukocytes
Isotype IgG2a kappa
Quantity 100µL
Regulatory Status RUO
Research Discipline Hematopoietic
Type Primary

Ensure accurate, reproducible results in immunohistochemistry , immunofluorescence, flow cytometry and function blocking experiments with Thermo Scientific™ CD36/GPIIIb/GPIV Ab-3, Mouse Monoclonal Antibody.

CD36 (also known as platelet glycoprotein IV, OKM5-antigen, or platelet glycoprotein IIIb) acts as a receptor for thrombospondin (TSP), collagen, falciparum malaria parasitized erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL), and apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischaemia observed in sickle cell disease and cerebral malaria. Ab-3 blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation.

Host Species: Mouse

Clone: 185-1G2

Isotype: IgG2a/κ

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Stimulated human leukocytes

Molecular Weight: 88 kDa

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Frozen only)
  • Western Blotting (Not suitable)
  • Immunofluorescence
  • Flow Cytometry
  • Function Blocking

Note:

USA: RUO; Int'l: RUO