missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

Thermo Scientific™ Lab Vision™ CD36/GPIIIb/GPIV Ab-3, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry , immunofluorescence, flow cytometry and function blocking experiment.

Manufacturer:  Thermo Scientific™ Lab Vision™ MS756P1ABX

 View more versions of this product

Catalog No. MS756P1ABX


 

Specifications

Description

Ensure accurate, reproducible results in immunohistochemistry , immunofluorescence, flow cytometry and function blocking experiments with Thermo Scientific™ CD36/GPIIIb/GPIV Ab-3, Mouse Monoclonal Antibody.

CD36 (also known as platelet glycoprotein IV, OKM5-antigen, or platelet glycoprotein IIIb) acts as a receptor for thrombospondin (TSP), collagen, falciparum malaria parasitized erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL), and apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischaemia observed in sickle cell disease and cerebral malaria. Ab-3 blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation.

Host Species: Mouse

Clone: 185-1G2

Isotype: IgG2a/κ

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Stimulated human leukocytes

Molecular Weight: 88 kDa

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Frozen only)
  • Western Blotting (Not suitable)
  • Immunofluorescence
  • Flow Cytometry
  • Function Blocking

Note:

USA: RUO; Int'l: RUO

Description & Specifications

Specifications

CD36/GPIIIb/GPIV Ab-3
Monoclonal
1mg/mL
Concentrated
Stimulated human leukocytes
100μL
Hematopoietic
Monoclonal
Flow Cytometry,Immunofluorescence,Immunohistochemistry (Frozen)
185-1G2
Unlabeled
Murine
IgG2a kappa
RUO
Primary
Human